British Air Force Typhoon jets have conducted a mission with French aircraft in a joint strike targeting an subterranean weapons facility in Syria employed by the IS group, according to the UK's MoD.
The facility, located using surveillance, was assessed as housing weapons and explosive materials, the release indicated, and was positioned in mountainous terrain just above Palmyra in central Syria.
"Our aircraft utilized laser-guided Paveway IV weapons to hit a number of entry passages providing entry to the facility... initial indications are that the strike was effective," the MoD said.
There was no evidence of any civilian casualties in the operation late on Saturday and all the aircraft returned safely, the MoD added.
The Typhoon FGR4s were assisted by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - enforced jihadist rule over large swathes of Syria and Iraq until 2019.
"This strike underscores the UK's leading role, and determination to stand shoulder to shoulder with our allies, to stamp out any resurgence of Daesh and their harmful and extremist ideologies in the area," UK Defence Secretary John Healey remarked.
RAF aircraft have conducted surveillance missions over Syria to "deter any efforts to regroup" of Islamic State subsequent to its routing at the Baghuz confrontation in the year 2019, the authorities noted.
"I want to thank every member of the UK armed forces who took part in this strike for their professionalism and their bravery," Healey added. "Including them were numerous British personnel deployed over Christmas and New Year. This operation, to remove militants who pose a risk to our way of life, demonstrates how British military are always on standby, all year round, protecting the UK at home and strong abroad."
Last December, the United States armed forces conducted what it called a "massive strike" against IS targets in the country, subsequent to an ambush resulted in the deaths of two US troops and a civilian interpreter in the Palmyra area.
The UN says Islamic State still has an estimated 5,000 to 7,000 militants in both countries.